Fusion of Inflammation and Regeneration Researches
نویسندگان
چکیده
منابع مشابه
Inflammation and axon regeneration.
PURPOSE OF REVIEW The inflammatory response that accompanies neural injury involves multiple cell types and effector molecules with both positive and negative effects. Inflammation is essential for normal regeneration in the peripheral nervous system, and here we review evidence that augmenting inflammation can enhance regeneration in areas of the central nervous system in which it normally doe...
متن کاملImmunohistochemical Assessment of Inflammation and Regeneration in Morphine-Dependent Rat Brain
Background: Opioids are amongst the most common abused drugs. Pathologic studies on opioid abuse are limited since the evaluation of inflammation and regeneration in brain tissue is not as simple as other tissues of the body. Thus, the present study aimed to determine the relationship between the dependence on morphine and inflammatory and regenerative processes. Methods: In this experimental s...
متن کاملPlatelets, inflammation and tissue regeneration.
Blood platelets have long been recognised to bring about primary haemostasis with deficiencies in platelet production and function manifesting in bleeding while upregulated function favourises arterial thrombosis. Yet increasing evidence indicates that platelets fulfil a much wider role in health and disease. First, they store and release a wide range of biologically active substances including...
متن کاملMini Review Inflammation and Regeneration
プロスタノイ ドは通常は細胞内に貯蔵されてお らず,細 胞内で必要 に応 じて合成,放 出され,そ の局所で多彩な作用 を発揮 し,生 体 のホメオスタ シスの維持 に関わる重要なオータコイドである. なかでも,生 体内において もっとも豊富に存在す るプ ロスタノイ ドであ るプロスタ グラ ンジン (PG)E2の 生理活性は血管拡張,胃 液分泌抑制,子 宮収縮,気 管支拡張,発 熱や発痛,炎 症反応など 多岐にわたっている.PGE2生 合成経路 はつぎの ような複数の酵素を介 した反応系で説明されてい る.す なわち,細 胞が生理的,病 理的なさまざま な刺激を受 けると,ホ スホ リパーゼA2(PLA2)に より生体膜 リン脂質からアラキドン酸が遊離され たあと,こ のアラキドン酸がシクロオキシゲナー ゼ(COX)に よりPGH,に 変換 される.さ らに,こ のPGH2がPG...
متن کاملInflammation, ageing, and bone regeneration
Summary Bone healing involves complex biological pathways and interactions among various cell types and microenvironments. Among them, the monocyte-macrophage-osteoclast line-age and the mesenchymal stem cell-osteoblast lineage are critical, in addition to an initial inflammatory microenvironment. These cellular interactions induce the necessary inflammatory milieu and provide the cells for bon...
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ژورنال
عنوان ژورنال: Ensho Saisei
سال: 2005
ISSN: 1346-8022,1880-5795
DOI: 10.2492/jsir.25.158